Great supplement for really active dogs. My dog, a young Lab who runs flyball, really benefits from all the enzymes and the creatine helps with joints not just muscle tone (some of the better arthitis supplements include it). Would give "5 paws" except the 400g packaging is too small to be economical for a large dog. At 90 lbs., my dog goes through it in just over a week at the recommended dose. Half the dosage seems to work just fine, but I wish BioSPORT came in 1600g like some of this manufacturer's other products.